首页|期刊导航|中国神经再生研究（英文版）|Skin nerve regeneration and burn wound healing following spinal nerve root incision
中国神经再生研究（英文版）2011，Vol.6Issue(8)：570-574,5.DOI:10.3969/j.issn.1673-5374.2011.08.002
Skin nerve regeneration and burn wound healing following spinal nerve root incision
Skin nerve regeneration and burn wound healing following spinal nerve root incision
摘要
Abstract
Burn wounds were produced on two sides on the backs of Wistar rats, in addition to denervation on one side. The skin neural regeneration at the injury site and burn wound healing were evaluated following spinal nerve root incision. No nerve regeneration was observed in the burn wound region post-denervation, and the degree of epithelization was significantly less than the control group. With increasing time, expression of type Ⅰ collagen, which plays a supporting role, and collagen Ⅲ, which exhibits elastic properties, were significantly increased in the two groups, but the expression was less in the denervation group compared with the control group, and the wound healing was faster in the control group. The ratio of type Ⅰ collagen to type Ⅲ collagen was significantly lower in the denervation group compared with the control group. The ratio gradually decreased with prolonged time in the denervation group, but remained unchanged in the control group. However, the elasticity of the tissues in the denervation group was better than the control group. During burn wound healing, innervations can promote wound healing, but denervation can improve the quality of wound remodeling.关键词
innervation/wound healing/collagen/scar/wound remodeling/neural regenerationKey words
innervation/wound healing/collagen/scar/wound remodeling/neural regeneration引用本文复制引用
Yibing Wang,Pengfei Guo,Yongqiang Feng,Yongqian Cao,Shourong Zhu,Rui Zhang..Skin nerve regeneration and burn wound healing following spinal nerve root incision[J].中国神经再生研究（英文版）,2011,6(8):570-574,5.基金项目
This study was supported by the Natural Science Foundation of Shandong Province (Changes of skin neural buildinq in normal human skin and scar tissue),No.Y2002C29. （Changes of skin neural buildinq in normal human skin and scar tissue）
