摘要
Abstract
Objective To explore the serum level and their clinical significance of high-sensitivity C- reactive protein(hs- CRP), soluble CXC chemokine iigand 16 (sol - CXCL16) and soluble vascular cell adhesion molecule - 1 ( sol - VCAM - 1 ) in patients with different coronary heart diseases(CHD). Methods Sixty one patients with CHD are randomized into acute coronary syndrome group(ACS group, 30 cases)and stable angina pectoris group(SAP group, 31 cases), and 30 volunteers are selected as controls. Serum levels of sol - CXCL16, sol - ICAM1 and hsCRP are measured by enzyme - linked immunosorbent assay. Results The Serum levels of sol - CXCL16( P＜ 0.05 ), sol - ICAM1 ( P ＜ 0.01 ) and hsCRP ( P ＜ 0.05) in ACS group are higher than that in SAP group, which in both groups are higher than that in control(P＜0.05 or P＜0.01). the level of sol - CXCL16 correlate with the levels of hsCRP, TG, CHO and LDL in all the selected ,while it correlate with the level of sol - ICAM1 only in ACS group. Conclusion To detect the Serum levels of sol - CXCL16, sol - ICAM1 and hsCRP has some clinical diagnosis and prognostic significance to coronary heart disease.关键词
冠状动脉疾病/动脉粥样硬化/炎症/CXC趋化因子配体16Key words
coronary heart disease/ artherosclerosis/ inflammation/ sol-CXCL16分类
医药卫生
