实用临床医药杂志2011，Vol.15Issue(5)：12-14,3.
鼻咽癌患者EBV感染与血管生成关系研究
Correlation between Epstern-Barr virus andangiogenesis of patients with nasopharyngeal carcinoma
摘要
Abstract
Objective To explore correlation between Epstein-Barr virus and angiogenesis of patients with nasopharyngeal carcinoma. Methods Epstein - Barr virus DNA of 54 patients with nasopharyngeal carcinoma was measured by PCR and their serum vascular endothelial growth factor (serum VEGF) level was also detected by ELISA, and these data was compared and analyzed with serum vascular endothelial growth factor level of 40 health control. Results Serum vascular endothelial growth factor level of 54 patients with nasopharyngeal carcinoma (143.86 ± 19.49) pg/mL was very higher than that of 40 health control (51.23 ± 12.66) pg/mL, (P＜0.01); Serum vascular endothelial growth factor level of 24 EBV positive patients with nasopharyngeal carcinoma (195.44 ± 19.69) pg/mL was remarkable higher than that of 30 EBV negative patients with nasopharyngeal carcinoma (154.58± 15.23 pg/mL), (P＜0.01). Conclusion Serum vascular endothelial growth factor level changed in patients with nasopharyngeal carcinoma may be as a new tumor mark for determining disease advancing about nasopharyngeal carcinoma.关键词
鼻咽癌/血清VEGF/EBV感染/血管生成Key words
nasopharyngeal carcinoma/ serum VEGF/ EBV infection/ angiogenesis分类
医药卫生引用本文复制引用
武要洪,李宝忠,李国萍,周永春,张楠,李佳..鼻咽癌患者EBV感染与血管生成关系研究[J].实用临床医药杂志,2011,15(5):12-14,3.基金项目
云南省教育厅资助课题(06Y135C) （06Y135C）
