四川医学2011,Vol.32Issue(4):510-512,3.
降调后血清雌激素水平预测IVF结局的价值
Evaluation of the predictive value for IVF outcomes of serum estrogen level after down regulation.
周瑞年 1王雪梅1
作者信息
- 1. 成都市妇女儿童中心医院生殖医学中心,四川,成都,610091
- 折叠
摘要
Abstract
Objective To investigate the predictive relevance for pregnancy outcomes of basal serum estrogen levels after pituitary down regulation during in-vitro fertilization (IVF) procedures.Methods To review total 202 IVF-ET cycles, which were down regulated by long protocol at mid-luteal phase, were retrospectively analyzed and were divided into 3 groups according to the basal serum estrogen levels on first day of ovarian hyper-stimulation, i.e.E2 < 15pg/ml group, 15pg/ml < E2 ≤30pg/ml group, and 30pg/ml < E2 ≤50pg/ml group.The predictive value of basal serum estrogen levels on first day of ovarian hyper-stimulation for IVF outcomes was analyzed.Results Gonadotropin consumption and days of ovarian stimulation were the least and numbers of oocyte obtained were the most in 15pg/ml < E2 ≤30pg/ml group, the drug consumption in the other 2 groups were relatively more and numbers of oocyte obtained were relatively less.There were no significant differences in gonadotropin doses, numbers of oocyte obtained, pregnancy rate and cycle cancellation rate between all three groups.Conclusion Patients in the group with 15pg/ml < E2 ≤30pg/ml on the first day of ovarian hyper-stimulation were associated with less gonadotropin consumption and more oocytes obtained, but the single measurement of E2 on the first day of ovarian hyper-stimulation is not sufficient for prediction of adverse reactions and pregnancy outcomes, more factors should he considered for this prediction.关键词
血清雌激素/卵巢不良反应/妊娠Key words
serum estrogen/ ovary adverse reaction /pregnancy分类
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周瑞年,王雪梅..降调后血清雌激素水平预测IVF结局的价值[J].四川医学,2011,32(4):510-512,3.