四川医学2011,Vol.32Issue(4):530-532,3.
格列美脲与瑞格列奈治疗初发2型糖尿病的疗效对比
Curative effect of glimepiride and repaglinide on early stage type 2 diabetes.
雷晓燕 1韩幸1
作者信息
- 1. 四川省第四人民医院内分泌科,四川,成都,610016
- 折叠
摘要
Abstract
Objective To compare the clinical effect of glimepiride and repaglinide on the early stage of type 2 diabetes.Methods 60 cases of type 2 diabetes were randomly divided into 2 groups, and treated with glimepiride ( n = 30 ) or repaglinid (n = 30) for 12 weeks.FBG、2hPBG、HbAlc、 FINS、2hPINS、FCP、2hPCP &BMI were measured before and after the treatment.The frequency of hypoglycemia event was observed for the duration.Results The levels of FBG,2hPBG & HbAlc in beth groups decreased obviously after 12-weeks treatment as compared with those at baseline ( P < 0.05 ).The treatment with repaglinide was more efficient than that with glimepiride in 2hPBG excursion in patients with type 2 diabetes( P < 0.05 ).The comparision of FBG、 HbAlc、FINS &FCP between two groups was no significant differenee(P > 0.05 ).Conclusion The efficacy of glimepiride or repaglinide is significant, so both of them are the first choice for patients with type 2 diabetes on the early stage.关键词
格列美脲/瑞格列奈/初发2型糖尿病Key words
glimepiride /repaglinide /the early stage of type 2 diabetes分类
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雷晓燕,韩幸..格列美脲与瑞格列奈治疗初发2型糖尿病的疗效对比[J].四川医学,2011,32(4):530-532,3.