中国药房2011，Vol.22Issue(18)：1683-1685,3.
我院2006-2009年328株鲍曼不动杆菌的分布与耐药性监测
Distribution and Drug Resistance Monitoring of 328 Strains of Acinetobacter baumannii of Our Hospital during 2006-2009
张望 1王路乔 1胡龙华1
作者信息
- 1. 南昌大学第二附属医院,南昌市,330006
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the clinical distribution and drug resistance of Acinetobacter baumannii, and to provide useful help for the treatment of A.baumannii infection.METHODS: A total of 328 nonduplicate strains of A.baumannii were collected from our hospital during 2006- 2009.All of isolated A.baumannii wers tested by Kirby-Bauer susceptibility.The drug susceptibility data was analyzed by WHONET 5.5 software.RESULTS: The samples were mainly from lower respiratory tract, accounting for 78.4％; the common drug resistance of A.baumannii were serious.The drug resistance rate of A.baumannii to Cefoperazone/sulbactam was the lowest, accounting for 10.5％; the drug resistance rates to imipenem, minocycline and amikacin were 40.1％,32.9％ and 56.1％, respectively; the drug resistance difference of isolated A.baumannii between ICU and other clinical department were remarkable, and the former was nearly twice higher than the latter.The detection rate of multi-drug resistant A.baumannii (MDR-AB) and pan-drug resistant A.baumannii (PDR-AB) increased year by year, from 70.4％ and 7.4％ in 2006 up to 73.9％ and 28.5％ in 2009.CONCLUSION: A.baumannii mainly distributes in sputum samples, and the infection in ICU is in serious condition.The detection rate and drug resistance rate is increasing.Cefoperazone/sulbactam, minocycline and carbapenems is the most effective agent against A.baumannii.The MDR-AB and PDR-AB is increasing significantly in recent two years, so it should be taken a high attention and the necessary prevention and control measures should be adopted.关键词
鲍曼不动杆菌/耐药性/监测分类
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张望,王路乔,胡龙华..我院2006-2009年328株鲍曼不动杆菌的分布与耐药性监测[J].中国药房,2011,22(18):1683-1685,3.
