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注射用盐酸甲砜霉素甘氨酸酯在4种输液中的配伍稳定性考察

韩强 王来成 云筠筠 胡丽丽 朱楠

中国药房2011,Vol.22Issue(18):1689-1690,2.
中国药房2011,Vol.22Issue(18):1689-1690,2.

注射用盐酸甲砜霉素甘氨酸酯在4种输液中的配伍稳定性考察

Compatible Stability of Thiamphenicol Glycinate Hydrochloride for Injection in 4 Kinds of Infusions

韩强 1王来成 1云筠筠 1胡丽丽 1朱楠2

作者信息

  • 1. 徐州医学院附属医院药剂科,徐州市,221002
  • 2. 徐州医学院药学院,徐州市,221004
  • 折叠

摘要

Abstract

OBJECTIVE: To study the compatible stability of Thiamphenicol glycinate hydrochloride (TGH) for injection in 4 kinds of infusions at different temperatures. METHODS: HPLC method was adopted to determine the contents of TGH for injection in Sodium lactate ringer injection, 5% Glucose injection, 0.9% Sodium chloride injection, Xylitol injection within 24 h at 5 ℃ and 25 ℃.The appearance and pH value of mixture were investigated. RESULTS: No significant changes of appearance, pH value or content of mixture had been observed within 24 h at 5 ℃ and 25 ℃. CONCLUSION: TGH for injection is compatible with 4 kinds of infusions at 5 ℃ and 25 ℃ for clinical use within 24 h.

关键词

盐酸甲砜霉素甘氨酸酯/输液/配伍/稳定性/高效液相色谱法

分类

医药卫生

引用本文复制引用

韩强,王来成,云筠筠,胡丽丽,朱楠..注射用盐酸甲砜霉素甘氨酸酯在4种输液中的配伍稳定性考察[J].中国药房,2011,22(18):1689-1690,2.

中国药房

OACSCDCSTPCD

1001-0408

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