中药材2011，Vol.34Issue(4)：572-575,4.
阿魏酸对bFGF诱导PC12细胞分化的影响
Effects of Ferulic Acid on bFGF-treated PC12 Cells
摘要
Abstract
Objective:To explore the effect and mechanism of ferulic acid on differentiation in bFGF-treated PC 12 cells. Methods:The length of neurite outgrowth and the percentage of PC12 cells induced in the presence of 0 ng/mL or 1 ng/mL bFGF were assayed. Results:Compared with that of control group,ferulic acid could enhance the differentiation effect of bFGF ( 1 ng/mL) in PC12 cells (P ＜0. 01 ) and the enhancing effect could be blocked by the specific MAPK kinase inhibitor,PD98059. Conclusion:Ferulic acid potentiates neurite outgrowth in bFGF-treated PC12 cells by MAPK-dependent signaling pathway.关键词
阿魏酸/PC12细胞/突起生长/bFGFKey words
Ferulic acid/ PC 12 cells/ Neurite outgrowth/ bFGF分类
医药卫生引用本文复制引用
林炼峰,肖飞,赖永长,苏锯年,罗焕敏..阿魏酸对bFGF诱导PC12细胞分化的影响[J].中药材,2011,34(4):572-575,4.基金项目
国家"211工程"建设经费资助 （）
