中药材2011，Vol.34Issue(4)：616-619,4.
星点设计-效应面法优选荷叶总生物碱超声提取工艺
Study on the Extraction of Total Alkaloid from Folium Nelumbinis with Ultrasonic Wave Technology Optimized by Central Composite Design and Response Surface Method
摘要
Abstract
Objective:To optimize the extracting process of Folium Nelumbinis by central composite design and response surface method. Methods: Independent variables were ethanol concentration, solvents ratio and pH, dependent variable was extracting rate of alkaloid. Composite design and response surface method were used to optimize the extracting process. Resultant model was used to predict the response in the optimal region. Results:The optimum extraction conditions were 80％ aqueous ethanol, 75 fold solvent, pH value 5. Conclusion :The optimum process is simple and more convenient for extracting Folium Nelumbinis. The observed and predicted values are close to each other.关键词
荷叶/总生物碱/星点设计/效应面法Key words
Folium Nelumbinis/ Total alkaloid/ Central composite design/ Response surface method分类
医药卫生引用本文复制引用
王福刚,曹娟,刘斌,王玉霞,高允生,陈静..星点设计-效应面法优选荷叶总生物碱超声提取工艺[J].中药材,2011,34(4):616-619,4.基金项目
"十一五"国家科技支撑计划项目(2006BAI08B03-04) （2006BAI08B03-04）
