首页|期刊导航|中国神经再生研究（英文版）|Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province
中国神经再生研究（英文版）2011，Vol.6Issue(9)：712-716,5.DOI:10.3969/j.issn.1673-5374.2011.09.013
Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province
Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province
摘要
Abstract
Currently it is not well known whether apolipoprotein E (ApoE) is a genetic susceptibility factor for cerebrovascular diseases in the Chinese Naxi population. The present study detected and sequenced ApoE polymorphisms of 90 patients with cerebrovascular diseases (58 cases of cerebral infarction and 32 cases of intracerebral hemorrhage), and 50 normal people of Naxi nationality from Yunnan province, China. The populations were used to analyze the relationship of ApoE polymorphisms with cerebral infarction and intracerebral hemorrhage. Results showed an association between ApoE gene polymorphism and the onset of cerebral infarction, and a possibility that the ε4 allele is a susceptibility locus for the risk of cerebral infarction. However, there was no evidence of a relationship between the ApoE gene polymorphism and cerebral hemorrhage.关键词
Apolipoprotein E/gene polymorphism/cerebrovascular disease/cerebral infarction/intracerebral hemorrhageKey words
Apolipoprotein E/gene polymorphism/cerebrovascular disease/cerebral infarction/intracerebral hemorrhage引用本文复制引用
Hong Xu,Qihong Yuan,Xijun Fan,Guoqiang He..Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province[J].中国神经再生研究（英文版）,2011,6(9):712-716,5.基金项目
the Scientific Research Foundation of Yunnan Provincial Science and Technology Department,Kunming Medical College,No.2008CD010 （）
