西南国防医药2011，Vol.21Issue(6)：592-594,3.DOI:10.3969/j.issn.1004-0188.2011.06.004
高原家兔胸部爆炸伤对血气及酸碱平衡的影响
Effects of thoracic explosive injury on blood gas and acid base balance in rabbits at high altitude
陈忠东 1李素芝 1王洪亚 1吴前进 1肖嘉芳 1易映红1
作者信息
- 1. 850003,拉萨,西藏军区总医院胸心外科
- 折叠
摘要
Abstract
Objective To study the changes of arterial blood gas and acid base balance in rabbits suffered from thoracic explosive injury at high altitude. Methods 24 rabbits were randomly divided into high - altitude injured group ( group A ), highaltitude control group ( group B ) and plain injured group ( group C ). In group A and C, a detonator was placed above the 5th right intercostal space of rabbit and exploded to cause the thoracic injury. In group B, animals were anesthetized and cannulated without thoracic injury. Blood samples were respectively collected before injury and at 1,3,6 h after injury for arterial blood gas analysis.Results After injury,each injured group showed persistent metabolic acidosis and lower blood gas parameters than those before injury ( P ＜ 0.05 or P ＜ 0.01 ). There were significant differences in each blood gas parameter between group A and C ( P ＜ 0.05 or P ＜0.01 ). Conclusion Decreased blood gas parameters and persistent metabolic acidosis are the most characteristic changes in rabbits suffered from thoracic explosive injury at high altitude. These changes are of significant value in the early treatment of such injury.关键词
高原/胸部/爆炸伤/酸碱平衡/血气分析分类
医药卫生引用本文复制引用
陈忠东,李素芝,王洪亚,吴前进,肖嘉芳,易映红..高原家兔胸部爆炸伤对血气及酸碱平衡的影响[J].西南国防医药,2011,21(6):592-594,3.
