广东医学2011,Vol.32Issue(12):1546-1547,2.
阿尔茨海默病患者血清C3、Aβ1-42测定及意义
Serum levels of complement C3 and Aβl -42 in patients with Alzheimer disease.
摘要
Abstract
Objective To evaluate serum complement C3 and Aβl - 42 in patients with Alzheimer disease ( AD ). Methods Serum samples of patients with Alzheimer disease and normal elders were collected for assessment of complement C3 and Aβl -42 using ELISA. Results Although higher level of complement C3 was revealed in AD group than that in controls, no significant difference was detected ( P > 0.05 ). However, significantly increase of Aβl -42 was revealed in AD group when comparing with that normal controls( P<0.05 ). Conclusion Serum Aβl-42 is a provides biochemical marker for the diagnosis of AD.关键词
阿尔茨海默病/补体C3/Aβ1-42Key words
Alzheimer's disease/ complement C3/ Aβl -42引用本文复制引用
张霞辉,李东风,王宝萍,向绍通,徐书雯..阿尔茨海默病患者血清C3、Aβ1-42测定及意义[J].广东医学,2011,32(12):1546-1547,2.基金项目
广东省医学科学基金资助项目(编号:C2009031),广州市科技计划项目(编号:2010Y1-C101) (编号:C2009031)