硅酸盐学报2011，Vol.39Issue(5)：825-828,4.
冷冻干燥法制备层状多孔羟基磷灰石支架过程中的溶剂升华行为
Solvent Sublimation Behavior in Freeze Drying Method for Lamellar Porous Hydroxyapatite Scaffold
摘要
Abstract
Lamellar porous hydroxyapatite (HA) ceramic scaffolds were fabricated by freeze drying from aqueous HA slurries and sintered at 1 250 ℃ for 3 h. Effects of freezing temperature, drying pressure and drying temperature on the solvent sublimation behavior were investigated. The average lamellar spacing of porous HA ceramic scaffolds decreases and the sublimation time increases with the decrease of freezing temperature. The sublimation time firstly decreases and then increases with the increase of the drying pressure due to the effect of heat and mass transfer in the drying process of HA scaffolds. The sublimation time deereases with increasing drying temperature. The optimum parameters in the freeze drying are drying pressure of 40 Pa and drying temperature of 5 ℃.The sublimation time of porous ceramics could be predicted based on the freezing temperature and drying parameters in the freeze drying.关键词
多孔材料/羟基磷灰石/冷冻干燥/冷冻温度/干燥参数/升华时间Key words
porous materials/ hydroxyapatite/ freeze drying method/ freezing temperature/ drying parameter/ sublimation time引用本文复制引用
汤玉斐,赵康,秦英谡,魏俊琪..冷冻干燥法制备层状多孔羟基磷灰石支架过程中的溶剂升华行为[J].硅酸盐学报,2011,39(5):825-828,4.基金项目
国家自然科学基金(50872110)及西安理工大学优秀博士论文基金(101-211002)资助项目. （50872110）
