农业环境科学学报2011，Vol.30Issue(5)：1027-1030,4.
泰乐菌素高效降解菌的筛选及降解特性研究
Isolation and Degradation Characteristics of a Tylosin-degrading Strain
摘要
Abstract
A mass of pharmaceutical waste is produced during tylosin production by fermentation. The resource utilization of pharmaceutical waste is restricted greatly because of the existence of antibiotic residue. The aim of this study was to investigate the degradation of tylosin residue in pharmaceutical waste by microbiological method. The results showed that a tylosin-degrading strain was isolated from the soil on which the tylosin pharmaceutical waste was long stacked. This strain was identified by 16S rDNA as Citrobacter amalonaticus. The optimal growth conditions of C. amalonaticus were at pH6.0～7.0 and temperature 30～35℃. The amount of 95.2 ％ of tylosin in medium was degraded by C. amalonaticus after fermentation for 48 h with conditions of initial bacteria concentration 10％, temperature 30℃, and pH 6.5. These indicate that tylosin residue in pharmaceutical waste can been degraded by using microorganism.关键词
泰乐菌素/无丙二酸柠檬酸杆菌/筛选/生物降解Key words
tylosin / citrobacter amalonaticus/ isolation/ biodegradation分类
资源环境引用本文复制引用
刘力嘉,谢丽,张作义,刘宁普,张新沙,马玉龙..泰乐菌素高效降解菌的筛选及降解特性研究[J].农业环境科学学报,2011,30(5):1027-1030,4.基金项目
国家自然科学基金项目(21067009) （21067009）
宁夏自然科学基金(NZ0819) （NZ0819）
宁夏大学科学研究基金项目(ZR200804) （ZR200804）
