分析测试学报2011，Vol.30Issue(5)：503-508,6.DOI:10.3969/j.issn.1004-4957.2011.05.006
气相色谱-正化学源质谱法测定家用橡胶手套中7种N-亚硝胺及其前体物的迁移量
Determination of Migration Levels of 7 N-nitrosamines and N-nitrosatable Substances from Household Gloves by Chromatography- Positive Chemical Ionization Mass Spectrometry
摘要
Abstract
A gas chromatography - positive chemical ionization mass spectrometric ( CC - PCI/MS)method was developed for the determination of migration levels of 7 N-nitrosamines and N-nitrosatable substances including N-nitrosodimethylamine ( NDMA), N-nitrosodiethylamine ( NDEA ), N-nitrosodi-n-propylamine ( NDPA), N-nitrosodi-n-butylamine ( NDBA ), N-nitrosopiperidine ( NPIP), N-nitrosopyrrolidine(NPYR) and N-nitrosomorpholine (NMOR) from household rubber gloves by using Sep-Pak AC2 connecting to Sep-Pak Dry cartridges. The developed method was simple, rapid, sensitive and accurate. Its quantitation limits for N-nitrosamines and N-nitrosatable substances were 1.25 μg/kg and 5.0 μg/kg, respectively. The total release values for the 7 N-nitrosatable substances were 6. 96- 168. 46 μg/kg, in which NDEA, NDMA and NDBA were found most frequently in 13 analysed household rubber gloves. The risk exposure levels of seven N-nitrosamines from household rubber gloves were in the class of 1.81 -43.80 μg per person in a year, which would bring a potent tial risk to people, especailly to some occupational population.关键词
气相色谱-正化学源/质谱法/手套/N-亚硝胺/前体物/迁移量Key words
gas chromatography - positive chemical ionization mass spectrometry ( GC - PCI/MS)/gloves/ N-nitrosamines/ N-nitrosatable substances/ migration level分类
化学化工引用本文复制引用
幸苑娜,王欣,陈泽勇,黄锦敏..气相色谱-正化学源质谱法测定家用橡胶手套中7种N-亚硝胺及其前体物的迁移量[J].分析测试学报,2011,30(5):503-508,6.基金项目
广东省质量技术监督局科技资助项目(2010CZ10) （2010CZ10）
