临床与实验病理学杂志2011，Vol.27Issue(6)：623-626,4.
粗针活检诊断子宫颈微偏腺癌4例及临床病理分析
Diagnosis of minimal deviation adenocarcinoma of cervix by core needle biopsy: a clinicopathologic analysis of 4 cases
李彦敏 1周奕琳 1郭雪西 1李艳 1章明放1
作者信息
摘要
Abstract
Purpose To describe the clinicopathologic , immunohistochemical and histochemical characteristics and differential diagnosis of cervical minimal deviation adenocarcinoma ( MDA ) examined by ultrasound-guided core needle biopsy, in order to investigate the advantages and feasihility of the methodology used in early diagnosis of cervical minimal deviation adenocarcinoma. Methods Four cases of ultrasound-guided core needle hiopsy of MDA were analyzed using HE , immunohistochemical and histochemical stains , also,compared with their radical resection specimens, respectively. Results The histopathologic characteristics MDA by of core needle biopsy was well-differentiated, adenocarcinoma with irregular glands and moderate atypia of epithelial cells in the fibrous stroma. and the interstitial fibrous tissue was proliferative change. Also, the irregular glands could be seen around large vessels. The atypia of epithelial cells were positive for CEA by immunohistochemical staining, and positive for AB/PAS by histochemical staining. The diagnosis of MDA was further confirmed by the radical resection specimens. Conclusions MDA sited in deep position ( ＞5 mm ) hy the ultrasound-guided core needle biopsy could satisfy the needs of pathologic diagnosis, and therefore this methodology used in early diagnosis of MDA has its advantages and feasibility.关键词
子宫颈肿瘤/恶性腺瘤/微偏腺癌/粗针活检Key words
uterine neoplasms/ adenoma malignum/ minimal deviation adenocarcinoma/ core needle biopsy分类
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李彦敏,周奕琳,郭雪西,李艳,章明放..粗针活检诊断子宫颈微偏腺癌4例及临床病理分析[J].临床与实验病理学杂志,2011,27(6):623-626,4.
