安徽农业科学2011，Vol.39Issue(6)：3274-3275,2.
五味子醇提物对小鼠肝脏抗氧化系统及微量元素含量的影响
Effects of Extract of FRUCTUS SCHISANDRAE CHINENSIS on the Hepatic Antioxidant System and Trace Elements in Mice
摘要
Abstract
[ Objective ] To study the effects of Extract of FRUCTUS SCHISANDRAE CHINENSIS on the hepatic antioxidant system and trace elements of mice. [ Methods] 40 male ICR mice were divided into control group and dose group with low, medium and high concentration randomly. Intragastric administration for 4 weeks, and then the content of reduced glutathione (GSH), malondialdehyde (MDA) and superoxide dismutase (SOD) in the hepatic tissue were determined. The hepatic tissue was digested by HNO3 - HClO4 mixed acid, and the contents of Zn, Cu, Fe and Mn etc. four trace elements in it were determined by atomic absorption spectrometry. [ Results ] The contents of GSH and SOD in medium dose group of Extract of FRUCTUS SCHISANDRAE CHINENSIS were obvious higher than that in the control group. The contents of Cu, Fe and Mn in medium and high dose groups of Extract of FRUCTUS SCHISANDRAE CHINENSIS were obvious higher than that in the control group. [ Conclusion ] Extract of FRUCTUS SCHISANDRAE CHINENSIS could enhance the hepatic antioxidant ability of mice significantly through maintaining the balance of trace elements in liver.关键词
五味子醇提物/小鼠/肝脏/抗氧化酶/微量元素Key words
Extract of FRUCTUS SCHISANDRAE CHINENSIS /Mice/Liver/Antioxidant enzyme/Trace elements分类
医药卫生引用本文复制引用
杜鹃,宋春梅,陈希,王琰..五味子醇提物对小鼠肝脏抗氧化系统及微量元素含量的影响[J].安徽农业科学,2011,39(6):3274-3275,2.基金项目
吉林省教育厅"十一五"科学研究项目(2008267). （2008267）
