帕利哌酮缓释片与国产奥氮平治疗精神分裂症的疗效及安全性观察OA北大核心CSCDCSTPCD
Observation of efficacy and safety of paliperidone sustained release tablets and domestic olanzapine in treatment of schizophrenia
目的 比较帕利哌酮缓释片与国产奥氮平治疗精神分裂症的疗效与安全性.方法 将符合CCMD-3的精神分裂症患者62例随机分为两组:治疗组(给予帕利哌酮缓释片)与对照组(给予国产奥氮平),随访观察12周.采用阳性和阴性症状量表(PANSS)及治疗不良反应量表(TESS)评价临床疗效与不良反应.结果 治疗组在治疗1周后各时间点的PANSS分值与治疗前PANSS分值比较差异有统计学意义(P<0.05);对照组在治疗2周后各时间点的PANSS分值与治疗前PA…查看全部>>
Objective To compare efficacy and safety of paliperidone sustained release tablets and domestic olanzapine in treatment of schizophrenia. Methods 62 patients with schizophrenia who met the diagnostic criteria of CCMD-3 were randomly divided into 2 groups:treatment group(treated with paliperidone sustained release tablets) and control group(treated with domestic olanzapine). 12-week followe-up observation was performed. Positive and negative syndrome scale …查看全部>>
曹国兴;谢国建
重庆市精神卫生中心老年一科,401147重庆市精神卫生中心老年一科,401147
精神分裂症帕利哌酮奥氮平
schizophrenia Paliperidone Olanzapine
《重庆医学》 2011 (17)
1695-1696,1758,3
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