中国当代儿科杂志2011，Vol.13Issue(4)：300-302,3.
90例儿童人博卡病毒感染临床分析
Clinical characteristics of human bocavirus infection in 90 children
摘要
Abstract
Objective To study the clinical characteristics of human bocavirus (HBoV) infection in children.Methods Nasal and throat swab samples were collected in 843 children with lower respiratory tract infection.The multiple RT-PCR method was used to detect HBoV and six other common respiratory tract viruses.The clinical characteristics of HboV positive cases were investigated.Results Among 843 cases, 90 were HboV positire ( 10.7％ ), 131 were respiratory syncytial virus (RSV) positive (15.5％), 117 were influenza virus positive (13.9％), 84 were parainfluenza virus positive (10.0％), 55 were rhinovirus positive (6.5％), 48 were coronavirus positive (5.7％), and 33 were hmnan metapneumovirus positive (3.7％).Of the 90 HBoV infected patients, 45 (50％) showed a co-infection with other respiratory tract viruses.Among them, 33 were infected with one other type of virus (37％), 11 ( 12％ ) were infected with two other types of virus, and 1 case ( 1％ ) was infected with other three viruses.The HBoV positive rate in children with wheezing was significantly higher than those without wheezing (17.0％ vs 9.2％; P＜0.01).The cormnon clinical manifestations of HBoV-infected patients included frequent coughing, wheezing and fever.There were no significant differences in the frequency of wheezing between HBoV and RSV infected patients.Conclusions HBoV positive rate detected from children with wheezing is higher than from children without wheezing, suggesting that apart from RSV, HBoV is another virus causing wheezing in children with respiratory tract infection.Co-infections of HBoV with other respiratory track viruses can be present in some patients.关键词
人博卡病毒/下呼吸道感染/喘息/儿童Key words
Human bocavirus/ Lower respiratory track infection/ Wheezing/ Child分类
医药卫生引用本文复制引用
严华杰,盛军,董蔚,邵洁..90例儿童人博卡病毒感染临床分析[J].中国当代儿科杂志,2011,13(4):300-302,3.基金项目
上海市卫生局青年科研项目(编号:2007Y77). （编号:2007Y77）
