基础医学与临床2011，Vol.31Issue(5)：574-577,4.
原发性肺非霍奇金淋巴瘤的临床特点及预后分析
Clinical characteristics and prognosis of primary pulmonary non-Hodgkin's lymphoma
李剑 1焦力 1张薇 1段明辉 1邹农 1周道斌 1沈悌1
作者信息
- 1. 中国医学科学院,北京协和医学院,北京协和医院,血液内科,北京,100730
- 折叠
摘要
Abstract
Objective To study the clinical characteristics and outcome of patients with primary pulmonary nonHodgkin's lymphoma (PPL). Methods The clinical features, diagnostic methods, pathological types and outcome of 30 patients with PPL diagnosed in PUMC Hospital were analyzed retrospectively. Results Of these 30 patients, 46. 7％ of patients were male and the median age was 46 years. These patients didn't have specific clinical symptoms and radiological features and 20％ patients were asymptomatic. The median time from onset to diagnosis of all patients was 8 months. The positive diagnostic rate of transbronchial lung biopsy, lung biopsy guided by computer tomography, and lung biopsy by thoracoscopy was 33. 3％, 50％ and 100％, respectively. The mucosa-associated lymphoid tissue (MALT) lymphoma was the main type in PLL, which was found in 56. 7％ patients. Seven of 30 patients died after 39 months of median follow-up time. Compared with patients with non-MALT lymphoma, patients with MALT lymphoma had lower international prognostic index (IPI) score and better prognosis. Conclusion The PPL is an uncommon extra-nodular lymphoma and is difficult to diagnose. The patients with non-MALT lymphoma have better prognosis in PPL.关键词
非霍奇金淋巴瘤/肺/原发性/临床特征Key words
non-Hodgkin's lymphoma/ lung/ primary/ clinical characteristics分类
医药卫生引用本文复制引用
李剑,焦力,张薇,段明辉,邹农,周道斌,沈悌..原发性肺非霍奇金淋巴瘤的临床特点及预后分析[J].基础医学与临床,2011,31(5):574-577,4.
