山东医药2011，Vol.51Issue(15)：36-38,3.
血清肿瘤标志物和肝功能指标联合检测在胰腺癌肝转移诊断中的价值
Vaule of co-detection of serum tumor markers and liver biochemical markers on the diagnosis of liver metastasis in patients with pancreatic cancer
马峰 1王学林 1吴雄志1
作者信息
- 1. 天津医科大学附属肿瘤医院,天津市卫生局中医药肿瘤生物调控重点研究室,天津,300171
- 折叠
摘要
Abstract
Objective To explore the predictive ability of tumor markers and liver biochemical markers for assessing liver metastasis in patients with pancreatic cancer. Methods The levels of serum tumor markers and liver biochemical markers in 125 patients ( 58 with liver metastasis,and 67 without)with pancreatic cancer were analyzed. Results For the patients with liver metastasis, the levels of CEA, CA19-9, CA242 and LDH were significantly higher than those for patients without liver metastasis ( P ＜ 0.05 ). The best cut-off points for CEA, CA19-9, CA242 and LDH to predict liver metastasis were 6.0 ug/L, 842 U/ml, 64 U/ml and 220 U/L, respectively. The sensitivity of CEA and LDH was 64.2％ and 51.9％, and the specificity was 71.4％ and 74.2％. The sensitivity and specificity of co-detection of CEA and LDH was 77.6％ and 93.5％. Conclusion The co-detection of tumor marker with the biochemical marker for liver has satisfactory sensitivity and specificity for screening pancreatic liver metastasis.关键词
胰腺癌/肝转移/肿瘤标志物Key words
pancreatic cancer/ liver metastasis/ tumor marker分类
医药卫生引用本文复制引用
马峰,王学林,吴雄志..血清肿瘤标志物和肝功能指标联合检测在胰腺癌肝转移诊断中的价值[J].山东医药,2011,51(15):36-38,3.
