河南农业科学2011，Vol.40Issue(3)：140-144,5.
河南地方野生小鼠遗传多样性分析
Genetic Analysis of Wild Mice in Henan Using Microsatellite Markers
摘要
Abstract
Fifty-six microsatellite makers have been engaged in the genetic analysis between four laboratory mice and wild mice strains in Henan province. A total of 230 alleles have been detected and the average alleles of each locus are 4. 107. The locus on D4Mit9 holds 8 different alleles,which is the most among all the 56 microsatellite markers. In contract, locus of D8Mit154,D7Mit8,D6Mit77,D17Mit244 and D18Mit119 has the least amount of alleles, which are two in average. Additionally, the average percentage of each locus in the wild mice is 68.98 ％ and 100％in the laboratory mice strains except the KM strain. The polymorphism analysis shows that the average polymorphism is 0. 657 0,0. 855 8,0. 919 7,0. 837 6 between wild mice and PWK,BALB/c,B6 and KM, respectively. At last, the cluster analysis shows that the genetic distance between wild mice and PWK strain is the nearest. This research states clearly that the wild mice in Lankao have a higher genetic diversity,which render the breeding research a great value and enlarge the gene resources of laboratory mouse.关键词
微卫星/野生小鼠/遗传多样性/河南省Key words
Microsatellite/ Wild mice/ Genetic diversity/ Henan province分类
生物科学引用本文复制引用
宋佳晟,王栋,雷建,赵卫东,郑振宇..河南地方野生小鼠遗传多样性分析[J].河南农业科学,2011,40(3):140-144,5.基金项目
河南省教育厅高校杰出科研人才创新工程项目(006KYCX015) （006KYCX015）
