中国内镜杂志2011，Vol.17Issue(4)：337-340,4.
经支气管针吸活检在ⅢA(N2)期非小细胞肺癌纵隔再分期中的作用
Value of mediastinal restaging for transbronchial needle aspiration in patients with N2 non-small cell lung cancer
摘要
Abstract
[Objective]To evaluate the value and safety of transbronchial needle aspiration (TBNA)for restaging the mediastinum in patients with N2 non-small cell lung cancer.[Methods]28 patients with stage ⅢA-N2 disease diagnosed by TBNA were treated with neoadjuvant chemotherapy.Mediastinal restaging by TBNA were performed after chemotherapy.All patients subsequently underwent pulmonary resection with Mediastinal lymph node dissection.[Results]On the basis of computed tomography, 12 (42.86％)patients were judged to have a partial response and 16 (57.14％) were classified as having stable disease.A diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of TBNA for mediastinal restaging after neoadjuvant chemotherapy were 77.08％, 100％, 100％, 42.11％ and 80.36％.Compared to the results before neoadjuvant chemotherapy (84.62％, 100％, 100％, 33.33％, 85.71％), there had no significant difference.[Conclusions]TBNA proved to be a safe procedure with a high yield for mediastinal lymph nodes restaging in patients with N2 non-small cell lung cancer.关键词
经气管镜针吸活检术/纵隔淋巴结/新辅助化疗Key words
TBNA/ mediastinal lymph nodes/ neoadjuvant chemotherapy分类
医药卫生引用本文复制引用
张嵩,彭忠民,姜淑娟..经支气管针吸活检在ⅢA(N2)期非小细胞肺癌纵隔再分期中的作用[J].中国内镜杂志,2011,17(4):337-340,4.基金项目
山东省科技发展计划项目No:2009GG10002061 （）
