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基于单胺类神经递质代谢谱研究姜黄和郁金的寒热药性差异

吴宏伟 李洪梅 唐力英 张东 杨洪军 黄璐琦

高等学校化学学报2011,Vol.32Issue(4):839-843,5.
高等学校化学学报2011,Vol.32Issue(4):839-843,5.

基于单胺类神经递质代谢谱研究姜黄和郁金的寒热药性差异

Heat and Cold Properties of Jianghuang and Yujin Based on Brain Catecholamine Metabolic Profiling

吴宏伟 1李洪梅 1唐力英 1张东 1杨洪军 1黄璐琦1

作者信息

  • 1. 中国中医科学院中药研究所,北京,100700
  • 折叠

摘要

Abstract

To compare and confirm different effects of Jianghuang and Yujin, a HPLC-MS method for the quantitative determination of 7 catecholamines in brain samples was developed. Principal component analysis (PCA) was processed to analyze the catecholamine metabolic profiling. The results suggested that heat-syn-drome model and cold-syndrome model could be distingushed by catecholamine metabolic profiling. Jiang huang and Yujin have different effects for the heat and cold syndrome model based on brain catecholamines metabolic profiling.

关键词

神经递质代谢谱/姜黄/郁金/寒热药性差异

Key words

Catecholamines metabolic profiling/ Jianghuang/ Yujin/ Heat and cold properties

分类

化学化工

引用本文复制引用

吴宏伟,李洪梅,唐力英,张东,杨洪军,黄璐琦..基于单胺类神经递质代谢谱研究姜黄和郁金的寒热药性差异[J].高等学校化学学报,2011,32(4):839-843,5.

基金项目

国家"九七三"计划项目(批准号:2006CB504701)资助. (批准号:2006CB504701)

高等学校化学学报

OA北大核心CSCDCSTPCD

0251-0790

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