色谱2011，Vol.29Issue(5)：422-425,4.DOI:10.3724/SP.J.1123.2011.00422
气相色谱-质谱法测定蜡笔中的芳香伯胺
Determination of primary aromatic amines in crayons by gas chromatography-mass spectrometry
摘要
Abstract
A method for the determination of nine primary aromatic amines in crayon by solid phase extraction (SPE) and gas chromatography-mass spectrometry (GC-MS) was developed.The alkanes in the sample were removed with n-hexane. Then the sample was extracted twice with ultrasonic extraction by methanol. The extract was evaporated, then the concentrated solution reacted with the reducing agent ( sodium hydrosulfite) for 30 min at 70 ℃. After the extraction with a diatomite SPE column, the aromatic amines were collected and separated on an HP-5M column, determined by MS. The nine primary aromatic amines can be separated and determined successfully. Under the optimized conditions, the detection limits were 5 mg/kg and the spiked recoveries of the samples were in the range of 86.02％ - 102.43％. The method is accurate and stable. It can be applied in the analysis of the primary aromatic amine of real crayon samples.关键词
固相萃取/气相色谱-质谱法/芳香伯胺/蜡笔Key words
solid phase extraction (SPE)/ gas chromatography-mass spectrometry (GC-MS)/primary aromatic amines/ crayon分类
化学化工引用本文复制引用
康苏媛,张庆,白桦,王超,吕庆..气相色谱-质谱法测定蜡笔中的芳香伯胺[J].色谱,2011,29(5):422-425,4.基金项目
国家财政部行业公益性项目(No.200810953). （No.200810953）
