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观察肿瘤标志物对预测乳腺癌复发转移的临床应用价值

陶四青 董浙清

中国临床药理学杂志2011,Vol.27Issue(6):414-416,3.
中国临床药理学杂志2011,Vol.27Issue(6):414-416,3.

观察肿瘤标志物对预测乳腺癌复发转移的临床应用价值

Clinical evaluation of tumor markers in the prediction of breast cancer recurrence and metastasis

陶四青 1董浙清2

作者信息

  • 1. 浙江中医药大学,附属第三医院外科,杭州,310005
  • 2. 浙江中医药大学,附属第三医院检验科,杭州,310005
  • 折叠

摘要

Abstract

Objective To investigate the clinical evaluation of tumor markers CA15 -3 and CA125 in the prediction of breast cancer recurrence and metastasis.Methods Using enzyme -linked immunosorbent assay (ELISA) to determine serum CA15 -3 and CA125 levels of 167 breast cancer patients before and after surgery as well as 80 healthy women.Results Serum CA15 -3 and CA125 levels are significantly higher in stage Ⅲ and Ⅳ patients than stage Ⅰ and Ⅱ patients and healthy women.The CA15 -3 levels increase evidently in patients of recurrence and metastasis.There is no difference between stage Ⅰ and Ⅱpatients and healthy women.Conclusion Tumor markers CA15 -3 and CA125 have important application in the evaluation of clinical stages and the prediction of recurrence and metastasis, however, they have no effectiveness in early diagnosis.

关键词

乳腺癌/肿瘤标志物/预测

Key words

breast cancer/ tumor markers/ prediction

分类

医药卫生

引用本文复制引用

陶四青,董浙清..观察肿瘤标志物对预测乳腺癌复发转移的临床应用价值[J].中国临床药理学杂志,2011,27(6):414-416,3.

中国临床药理学杂志

OA北大核心CSCDCSTPCD

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