中国医疗设备2011，Vol.26Issue(5)：1-15,15.DOI:10.3969/j.issn.1674-1633.2011.05.001
生物组织弹性测量:技术、仪器和应用
Soft Tissue Elasticity Measurement: Techniques, Instrument and Applications
摘要
Abstract
Clinically it is generally known that palpation can be used to detect the existence of hard lesion in soft tissues for a first-step diagnosis, such as the detection of breast cancer. However, palpation can only give qualitative results, which quite depend on the experience of the operator and suffer from diagnosis subjectivity. To address this problem, more quantitative and objective tools, i.e. elasticity imaging and elasticity measurement techniques have been developed. These two techniques have their own characteristics: elasticity imaging normally gives information related to the contrast of elasticity while no intrinsic properties are provided for the detected tissue; in contrast, elasticity measurement gives an absolute value for the intrinsic elastic properties of the tissue, such as Young's modulus, which will be helpful for the diagnosis of diffused diseases such as liver fibrosis and their longitudinal follow-up. Furthermore, the obtained results do not or less depend on the instrument used. Consequently, with the broad applications of various medical imaging modalities, such as ultrasound, magnetic resonance imaging (MRI) and optical imaging techniques, the field of elasticity measurement is developing fast in the last two to three decades, generating a large number of new techniques and instrument, among which some clinical trials are ongoing. It is expected that with the further development of the currently existing techniques and the emergence of new methods, the elasticity measurement will be more widely tested and applied to clinical fields. The elasticity measurement can be used to complement the currently imperfect diagnosis of some diseases or to evaluate the effectiveness of the treatment strategies. In this review, we will firstly introduce the traditional and recently developed tissue elasticity measurement techniques and then their applications for the diagnosis of diseases and evaluation of therapy are overviewed. Finally some future research directions and perspective of this field are presented. For some relatively matured techniques, we will introduce them in more details in coming issues of this journal.关键词
弹性/弹性测量/弹性成像/杨氏模量/粘弹性/力学测试/印压/超声/剪切波/传播速度Key words
Elasticity/ elasticity measurement/ elasticity imaging/ elastography/ Young's modulus/ viscosity/ mechanical test/ indentation/ ultrasound/ shear wave/ propagation speed分类
医药卫生引用本文复制引用
郑永平,黄燕平..生物组织弹性测量:技术、仪器和应用[J].中国医疗设备,2011,26(5):1-15,15.基金项目
香港研究资助局(PolyU5354/08E)和香港理工大学(J-BB69)支持. （PolyU5354/08E）
