实用临床医药杂志2011，Vol.15Issue(7)：47-50,4.
剖宫产术布比卡因扩散与脑脊液生化特性的关系
The relationship between biochemical characteristics and bupivacaine drug spread in CSF for Caesarean section
叶桂云 1李智海 1胡望平 2池细递 1张忠源 1陈丽娟 1林坚 1姜闽英1
作者信息
- 1. 福建医科大学附属南平第一医院,福建南平,353000
- 2. 南京军区福州总医院,福建福州,350025
- 折叠
摘要
Abstract
Objective To investigate the relationship between biochemical characteristics and isobaric bupivacaine drug spread for Caesarean section in cerebrospinal fluid (CSF). Methods A total dose of 3 mL isobaric admixture of cerebrospinal fluid and 15 mg bupivacaine (Caesarean section 10 mg bupivacaine) in lumbar anesthesia were administered. The comparisons of cerebrospinal fluid osmotic pressure et al five item index and the extent of spinal block of Bupivaeaine in 100 cases of Cesarean delivery and 58 cases of non - pregnant female, 61 cases of male and 58 cases of non - pregnant female, 22 cases of menopausal female and 36 cases of premenopausal female have been conducted. Results Cerebrospinal fluid chlorine, total proteins concentrations were significantly different in male patient than female ( P ＜ 0.05). Cerebrospinal fluid osmotic pressure, total proteins, sodium concentrations, and age on spinal anaesthesia were significantly lower, but the extent of spinal block was significantly higher in cesarean delivery than in women ( P ＜ 0. 001 ), it was manifested among the total difference of cerebrospinal fluid osmotic pressure( F = 37. 466). There were no difference except age in all biochemical characteristics index between menopausal female and premenopausal female (P ＞0.05). Conclusion A correlation between cerebrospinal fluid osmotic pressure and the extent of spinal block with plain bupivacaine is found in 100 cesarean delivery patients (A = 44.46 - 0.13B, r = 0. 339).关键词
剖宫产/脑脊液/脊髓阻滞程度/渗透压/布比卡因/腰麻Key words
cesarean delivery/ cerebrospinal fluid/ the extent of spinal block/ the osmotic pressure/ isobaric bupivacaine/ lumbar anesthesia分类
医药卫生引用本文复制引用
叶桂云,李智海,胡望平,池细递,张忠源,陈丽娟,林坚,姜闽英..剖宫产术布比卡因扩散与脑脊液生化特性的关系[J].实用临床医药杂志,2011,15(7):47-50,4.
