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一株拟青霉菌(Paecilomyces sp.)的次生代谢产物研究

张永刚 袁文鹏 夏雪奎 贾爱荣 刘新 张绵松 刘昌衡

中药材2011,Vol.34Issue(5):707-709,3.
中药材2011,Vol.34Issue(5):707-709,3.

一株拟青霉菌(Paecilomyces sp.)的次生代谢产物研究

The Study of the Secondary Metabolites from Fungus Paecilomyces sp.

张永刚 1袁文鹏 2夏雪奎 1贾爱荣 2刘新 2张绵松 1刘昌衡2

作者信息

  • 1. 山东省科学院中日友好生物技术研究中心/山东省应用微生物重点实验室,山东,济南,250014
  • 2. 山东省科学院生物研究所,山东,济南,250014
  • 折叠

摘要

Abstract

Objective:To get active secondary metabolites from the fungus Paecilomyces sp.. Methods:The strain Paecilomyces sp. was further grown in solid-substrate fermentation cultures, the metabolites were got by application of different separation techniques,such as silica gel ,Sephadex LH-20 column chromatography,and reversed-phase high performance liquid chromatography. Their structures were identified by comprehensive spectroscopic methods. Results:Four compounds were isolated and identified as Cerebroside C ( 1 ), Cerebroside D (2), 2-Hydroxybenzyl alcohol ( 3 ), 2-( 4-Hydroxyphenyl ) ethanol . Conclusion: Four compounds are isolated from Paecilomyces sp. for the first time.

关键词

海蜇/共附生真菌/次生代谢产物

Key words

Paecilomyces sp. /Fungus/Secondary metabolites

分类

医药卫生

引用本文复制引用

张永刚,袁文鹏,夏雪奎,贾爱荣,刘新,张绵松,刘昌衡..一株拟青霉菌(Paecilomyces sp.)的次生代谢产物研究[J].中药材,2011,34(5):707-709,3.

基金项目

国家自然科学基金青年基金(31000008) (31000008)

山东省优秀中青年科学家奖励基金资助项目(BS2010HZ019) (BS2010HZ019)

山东省科学院博士基金(ZBS2010Y) (ZBS2010Y)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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