中国美容医学2011，Vol.20Issue(z2)：521,523,2.
肺炎克雷伯菌医院感染现状及耐药性分析
Distribution and Antibiotic Resistance of Klebsiella pneumoniae in Hospital of 2010
冯涛 1何士彦 1安翠萍 1霍卫池 1任晓华 1丁秋蕾 1杨慧芳 1彭雯1
作者信息
- 1. 石家庄市中心医院,河北,石家庄,050011
- 折叠
摘要
Abstract
Objective: To investigate the distribution and situation of antibiotic resistance of klebsiella pneumoniae isolated from our hospital in 2010, so as to provide reference for antimicrobial treatment. Methods:A total of 448 strains of klebsiella pneumoniae were retrospectively analyzed according to the source of specimens, infections in different departments and drug-resistance. Results: More than 96. 0％ klebsiella pneumoniae were found to be sensitive to the carbopenems (ie. imipenem and meropenem) as well as those compound preparations (ie. cefoperazone/sulbactsm and piperacillin/tazobactam). However, to other kinds of antibiotic drugs, the drug resistance of klebsiella pneumoniae was serious. In the investigation, the highest resistance rate of klebsiella pneumoniae was present in the penicillins as ampicillin and the cephalosporins as cefazolin, cefuroxime, ceftriaxone and cefotaxime, all of them showed a critical drug resistance (more than 50. 0％). Simultaneously, to amikacin, isepamicin and levofloxacin, ciprofloxacin, which respectively belonging to aminoglycosides and quinolones, a lower resistance rate of klebsiella pneumoniae varied from 20. 0％ to 30.0％ was confirmed. Conclusion:Klebsiella pneumoniae, isolated from the patients, has shown a high rate of resistance to routine antimicrobial agents, and even has presented multiple antibacterial resistance. So we must keep an eye on the nosocomial infection and rationally use the antimicrobial agents in order to decrease or delay the production of multi-drug resistant atrains.关键词
肺炎克雷伯菌/医院感染/耐药性/起广谱β-内酰胺酶Key words
Klebsiella pneumoniae/ Nosocomial infection/ Drug resistance/ ESBLs分类
医药卫生引用本文复制引用
冯涛,何士彦,安翠萍,霍卫池,任晓华,丁秋蕾,杨慧芳,彭雯..肺炎克雷伯菌医院感染现状及耐药性分析[J].中国美容医学,2011,20(z2):521,523,2.
