摘要
Abstract
Objective: To investigate the value of dual source CT perfusion imaging parameters, including blood volume (BV), blood flow(BF), and Pat[ak P value in evaluating the biological behavior of gastric carcinoma.Methods: Dual source CT perfusion imaging was performed in 98 patients of gastric carcinoma.The BV, BF, Patlak P value were obtained to study the relationship between the parameters of perfusion and the biological behavior in gastric cancer, and estimate the value of parameters.Results: The BF could predict gastric carcinoma had no distant metastasis with a sensitivity of 72.13%, a specificity of 64.52%, a positive predictive value of 81.67%, a negative predictive value of 52.63%, and an accuracy of 70.41%.The BV could predict the gastric carcinoma had no distant metastasis with a sensitivity of 68.66%, a specificity of 51.61%, a positive predictive value of 75.41%, a negative predictive value of 43.24%, and an accuracy of 63.27%.The BV could predict gastric carcinoma confined within the serous membrane with a sensitivity of 60.00%, a specificity of 69.57%, a positive predictive value of 86.54%, a negative predictive value of 34.78%, and an accuracy of 62.24%.Patlak P value could predict the gastric carcinoma confined within the muscularis with a sensitivity of 61.54%, a specificity of 75.86%, a positive predictive value of 69.57%, a negative predictive value of 68.75%, and an accuracy of 69.09%.Patlak P value also could predict the gastric carcinoma had protrude beyond the serous membrane with a sensitivity of 14.29%, a specificity of 69.23%, a positive predictive value of 60%, a negative predictive value of 20%, and an accuracy of 27.27%.Conclusion: The dual source CT perfusion imaging parameters could assess the biological behavior of gastric carcinoma, but there still has limitations.关键词
胃肿瘤/体层摄影术,X线计算机Key words
Stomach neoplasms/ Tomography, X-ray computed分类
医药卫生