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双源CT灌注参数评估胃癌生物学行为的诊断试验研究

李春志 徐荣天 于晓晶 张元元 金焱

中国临床医学影像杂志2011,Vol.22Issue(6):406-409,4.
中国临床医学影像杂志2011,Vol.22Issue(6):406-409,4.

双源CT灌注参数评估胃癌生物学行为的诊断试验研究

The research of dual source CT perfusion parameter in biological behavior of gastric carcinoma

李春志 1徐荣天 2于晓晶 1张元元 1金焱1

作者信息

  • 1. 中国中医科学院西苑医院放射科,北京,100091
  • 2. 中国医科大学附属第一医院放射科,辽宁,沈阳,110001
  • 折叠

摘要

Abstract

Objective: To investigate the value of dual source CT perfusion imaging parameters, including blood volume (BV), blood flow(BF), and Pat[ak P value in evaluating the biological behavior of gastric carcinoma.Methods: Dual source CT perfusion imaging was performed in 98 patients of gastric carcinoma.The BV, BF, Patlak P value were obtained to study the relationship between the parameters of perfusion and the biological behavior in gastric cancer, and estimate the value of parameters.Results: The BF could predict gastric carcinoma had no distant metastasis with a sensitivity of 72.13%, a specificity of 64.52%, a positive predictive value of 81.67%, a negative predictive value of 52.63%, and an accuracy of 70.41%.The BV could predict the gastric carcinoma had no distant metastasis with a sensitivity of 68.66%, a specificity of 51.61%, a positive predictive value of 75.41%, a negative predictive value of 43.24%, and an accuracy of 63.27%.The BV could predict gastric carcinoma confined within the serous membrane with a sensitivity of 60.00%, a specificity of 69.57%, a positive predictive value of 86.54%, a negative predictive value of 34.78%, and an accuracy of 62.24%.Patlak P value could predict the gastric carcinoma confined within the muscularis with a sensitivity of 61.54%, a specificity of 75.86%, a positive predictive value of 69.57%, a negative predictive value of 68.75%, and an accuracy of 69.09%.Patlak P value also could predict the gastric carcinoma had protrude beyond the serous membrane with a sensitivity of 14.29%, a specificity of 69.23%, a positive predictive value of 60%, a negative predictive value of 20%, and an accuracy of 27.27%.Conclusion: The dual source CT perfusion imaging parameters could assess the biological behavior of gastric carcinoma, but there still has limitations.

关键词

胃肿瘤/体层摄影术,X线计算机

Key words

Stomach neoplasms/ Tomography, X-ray computed

分类

医药卫生

引用本文复制引用

李春志,徐荣天,于晓晶,张元元,金焱..双源CT灌注参数评估胃癌生物学行为的诊断试验研究[J].中国临床医学影像杂志,2011,22(6):406-409,4.

中国临床医学影像杂志

OACSTPCD

1008-1062

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