中国美容医学2011，Vol.20Issue(z2)：64-65,2.
预先注射瑞芬太尼预防小儿静注罗库溴铵时的回避反应
Pretreatment with remifentanil to prevent withdrawal after rocuronium in children
刘永梁 1刘丽 1周旋1
作者信息
- 1. 黑龙江牡丹江医学院红旗医院,黑龙江,牡丹江,157000
- 折叠
摘要
Abstract
Objective:This study was designed to evaluate the efficacy of pretreatment with i.v.remifentanil on prevention of withdrawal response during rocuronium injection in paediatric patients.Methods:After obtaining parental consents, 40 paediatric patients were randomly allocated into two groups to receive either i.v.remifentanil 1 mg/kg(remifentanil group, n=20) or i.v.saline 5 ml (saline group, n=20).Anaesthesia was induced with thiopental sodium 2.5％ (5 mg/kg) and the test drug was injected over 30 s.One minute after the test drug injection, rocuronium 1％(0.6 mg/ kg) was injected over 5 s and the response was recorded.Mean arterial pressure (MAP) and heart rate were recorded on arrival in the operating theatre, before and 1 min after thetracheal intubation.Results:The overall incidence of withdrawal movements was significantly higher in the saline group (19 patients; 95％) than that in the remifentanil group (5 patients; 25％) (P＜0.001).No patient in the remifentanil group showed generalized movement, whereas 55 ％ of patients in the saline group did.Remifentanil prevented significant increase in MAP after intubation.Conclusion: This study demonstrated that pretrestment with remifentanil 1 ug/kg provided a safe and simple method for reducing the incidence of rocuronium-associated withdrawal movement with haemodynsmic stability in children.关键词
小儿/瑞芬太尼/罗库溴铵Key words
paediatric/ remifentanil/ rocuronium分类
医药卫生引用本文复制引用
刘永梁,刘丽,周旋..预先注射瑞芬太尼预防小儿静注罗库溴铵时的回避反应[J].中国美容医学,2011,20(z2):64-65,2.
