重庆医学2011，Vol.40Issue(23)：2327-2329,3.DOI:10.3969/j.issn.1671-8348.2011.23.015
儿童B系急性淋巴细胞白血病CD20表达及临床意义
Clinical significance of children with CD20 antigen expression in B acute lymphoblastic leukemia
何云燕 1罗建明 1蒋玉凤2
作者信息
- 1. 广西医科大学附属第一医院儿科,南宁,530021
- 2. 广西医科大学研究生学院,南宁,530021
- 折叠
摘要
Abstract
Objective To investigate the relationship between the expression of CD20 antigen in children with B acute lymphoblastic leukemia(B ALL) at first diagnosis and clinical characteristics. Methods The expression of CD20 antigen was measured in 120 patients who were the first diagnosis in hematopathy sickroom of the First Affiliated Hospital of Guangxi Medical University from July 2006 to Aug 2010 using direct immunofluorescence scan. Results Positive rate of 120 patients with CD20 antigen expression was 25％. No significant relationships were found between CD20 antigen expression and gender,age,peripheral blood leucocytes count, hemoglobin level, platelet count, FAB classification, chromosomal changes, central nervous system leukemia at diagnosis,marrow status of remission induction chemotherapy on day 19 and clinical risk classification. Conclusion Patients with CD20 + and CD20 in B ALL at first diagnosis are the same clinical characteristics and do not have more high risk characteristics.关键词
白血病,淋巴细胞性/急性/抗原,分化/流式细胞术Key words
Leukemia/ lymphocytic/ acute/ antigen/ differentiation/ flow cytometry引用本文复制引用
何云燕,罗建明,蒋玉凤..儿童B系急性淋巴细胞白血病CD20表达及临床意义[J].重庆医学,2011,40(23):2327-2329,3.
