日用化学工业2011，Vol.41Issue(3)：229-231,3.
高效液相色谱法同时测定化妆品中的4种禁用着色剂
Simultaneous determination of four forbidden colorants in cosmetics by HPLC
郭桂媛 1林维宣 2金红利 1于一茫 2侯红漫1
作者信息
- 1. 大连工业大学,辽宁大连116034
- 2. 辽宁省出入境检验检疫局,辽宁大连116001
- 折叠
摘要
Abstract
A new high performance liquid chromatography/ultraviolet -visible detector (HPLC/UV -Vis) method was developed for the simultaneous determination of four forbidden colorants in cosmetics. The cosmetic sample was extracted using ethanol as solvent and the extract was analyzed by HPLC using a C18 reversed -phase column (5 μm,250 mm ×4.6 mm) with gradient elution using acetonitrile (A) and 0. 5％ H3PO4 (B) as mobile phase. The quantitative analysis was carried out by external standard method using UV - Vis as detector with detection wavelength at 530 nm. The LODs of Basic Violet 1, Pigment Orange 5, Sudan Blue 2 and Sudan Red IV were identified as 0. 05,0. 5,0. 5,0. 2 μg/mL respectively. The average recoveries of four colorants range from 86％ to 100％ with RSDs of 3.68％ ～ 8.02％.关键词
化妆品添加剂/高效液相色谱法/着色剂Key words
cosmetics additives/ HPLC/ colorants分类
化学化工引用本文复制引用
郭桂媛,林维宣,金红利,于一茫,侯红漫..高效液相色谱法同时测定化妆品中的4种禁用着色剂[J].日用化学工业,2011,41(3):229-231,3.
