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胃癌患者血脂、脂蛋白、血清CEA及CA199检测

景晓刚 王贵吉 裴迎新 吴晶晶

郑州大学学报(医学版)2011,Vol.46Issue(3):432-435,4.
郑州大学学报(医学版)2011,Vol.46Issue(3):432-435,4.

胃癌患者血脂、脂蛋白、血清CEA及CA199检测

Detection of blood lipid, lipoprotein metabolism and serum CEA, CA199 of gastric carcinoma patients

景晓刚 1王贵吉 2裴迎新 3吴晶晶2

作者信息

  • 1. 中平能化集团总医院肿瘤科,平顶山,467000
  • 2. 郑州大学第一附属医院肿瘤科,郑州,450052
  • 3. 郑州大学公共卫生学院营养与食品卫生学教研室,郑州,450001
  • 折叠

摘要

Abstract

Aim: To detect the serum levels of blood-lipid, lipoprotein, carcinoembryonic antigen (CEA) and carbohydrate antigen(CA199) of gastric carcinoma patients. M6thodS:A total of 158 cases of gastric cancer, including 62 cases treated only by chemotherapy directly(38 metastasis cases and 24 no metastasis cases) and 96 cases treated operation and adjuvant chemotherapy (15 cases in pathologic stage I , 25 cases in stage II , 33 cases in stage M , 23 cases in stage IV ) , were to detect the serum levels of TG, TC, HDL, LDL, CEA,and CA199. 100 normal casesand 80 cases of benign disease ( gastritis and gastric ulcer) were the controls. Results: The levels of TG, CEA, CA199 in gastric cancer group were higher than those in the other two groups (P<0.05), while the levels of TC, HDL, LDLwere lower (P<0. 05). The levels of TC, LDL of gastric cancer group after operation were higher than those before operation (t = 20. 315 ,24. 557 , P < 0.001) . Differences in the levels of TC ,HDL,LDL,CEA,CA199 among different pathologic stages were significant in gastric cancer group ( P < 0. 05). The levels of the indexes mentioned above were not related with the therapy ( P > 0. 05 ) . Conclusion: Blood-lipid and lipoprotein could be helpful for the diagnosis and adjudging the stages of clinical pathology of gastric cancer.

关键词

胃癌/血脂/脂蛋白/CEA/CA199

Key words

gastric carcinoma/ blood lipid/lipoprotein/CEA/CA199

分类

医药卫生

引用本文复制引用

景晓刚,王贵吉,裴迎新,吴晶晶..胃癌患者血脂、脂蛋白、血清CEA及CA199检测[J].郑州大学学报(医学版),2011,46(3):432-435,4.

郑州大学学报(医学版)

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