摘要
Abstract
Objective To investigate the influence of plasminogen combined hyperbaric oxygen therapy on prognosis and coagulation in patients with acute cerebral infarction.Methods 86 patients with acute cerebral infarction were randomly divided into two groups, hyperbaric oxygen combined fibrinolytic therapy( HBD group, n= 40 cases ) and hyperbaric oxygen therapy ( non-HBO group, n =46 cases ) were given respectively.Indexes of two groups of patients with coagulation, neurological deficit score and overall efficacy were recorded and analyzed.Results After treatment, the total efficacy in hyperbaric oxygen group( 92.5％ )was significantly higher than non-HBO group ( 73.9％ ), the difference was statistically significant ( P ＜ 0.05 ).compared with before treatment, PT, APTT prolonged, and TT shortened in the 2 groups after treatment.Fib levels decreased and neurological deficit scores were significantly lower, the differences between them were statistically significant( P ＜ 0.05 ), the hyperbaric oxygen group were superior to the non-HBO group( P ＜ 0.05 ).Conclusion Plasmin combined hyperbaric oxygen therapy is a effective and safe method on the coagulation of acute cerebral infarction, the neurological deficit score and overall effect were improved obviously.关键词
纤溶酶/高压氧/脑梗死,急性期/凝血功能/预后Key words
Plasminogen/ Hyperbaric oxygen/ Cerebral infarction, acute phase/ Coagulation/ Prognosis
