高等学校化学学报2011，Vol.32Issue(6)：1289-1294,6.
纳升电喷雾萃取电离质谱快速测定人参皂苷
Rapid Detection of Ginsenosides Using NanoEESI-MS
摘要
Abstract
A novel method for rapidly detecting ginsenosides was developed based on nano electrospray extractive ionization(NanoEESI) tandem mass spectrometry. Without any chromatographic separation, the raw extract of ginseng roots were directly introduced to the gasless NanoEES1 source for production of sodiated ions of ginsenosides. The signals of sinsenosides [ M + Na] + were identified by tandem mass spectrometry. The characteristic fragmentation patterns were therefore used as molecular markers to differentiate ginseng roots from platycodon grandiflorum and phytolacca acinosa rox, which are two typical plant roots illicitly used as ginseng roots in the herb medicine market. Acceptable sensitivity, reproducibility and fast speed were obtained for the tested samples, showing that nano extractive electrospray ionization tandem mass spectrometry is a useful technique for fast screening ginseng products or other traditional Chinese medicinal materials.关键词
纳升电喷雾萃取电离/质谱/人参皂苷/快速分析Key words
NanoEESI/ Mass spectrometry/ Ginsenosides/ Rapid analysis分类
化学化工引用本文复制引用
胡斌,越皓,黄科科,姜翠翠,刘淑莹,费强,陈焕文..纳升电喷雾萃取电离质谱快速测定人参皂苷[J].高等学校化学学报,2011,32(6):1289-1294,6.基金项目
国际科技合作项目(批准号:2009DFA30800)和江西省科技支撑计划项目(批准号:105)资助. （批准号:2009DFA30800）
