中国临床保健杂志2011，Vol.14Issue(3)：275-277,3.DOI:10.3969/J.issn.1672-6790.2011.03.020
银杏达莫注射液对糖尿病大鼠唾液腺组织脂质过氧化作用的影响
The effect of Gingko Biloba extract on lipid peroxidation in parotid gland and submandibular gland of diabetic rats
摘要
Abstract
Objective To study the effects of Extract Cingko biloga ( EGb) on lipid peroxidation in parotid gland and submandibular gland of diabetic rats. Methods Strepozotocin were injected intraperitoneally into Wistar rats accompanied with high fat and high glucose food to induce diabetes mellitus. The content of malondiadehyde ( MDA) ,the total activity of superoxide dismutase ( T-SOD) and total antioxidant capacity ( T-AOC) were investigated in parotid gland and submandibular gland. Results Diabetic rats showed a decrease in the content of MDA in the parotid gland, but an increase in the submandibular gland. No difference in the activity of T-SOD in either group rats was observed in either gland. T-AOC showed higher capacity in the parotid gland of the diabetic rats than control,however,in the submandibular gland, no difference was observed. After treatment by EGb, the parotid gland showed an increase in the capacity of T-AOC , however, for the submandibular gland , no difference statistically significant was observed. Conclusion A difference of lipid peroxidation was observed in parotid gland and submandibular gland of type 2 diabetic rats. EGb could increase antioxidation effect in parotid gland but not in submandibular gland of diabetic rats.关键词
糖尿病,2型/过氧化脂质类/链脲菌素/大鼠,wistarKey words
Diabetes mellitus , type 2 / Lipid peroxides / Strepotozocin / Rats, wistar分类
医药卫生引用本文复制引用
滕艳杰,陈培,冯华,王莞,李丽颖..银杏达莫注射液对糖尿病大鼠唾液腺组织脂质过氧化作用的影响[J].中国临床保健杂志,2011,14(3):275-277,3.基金项目
黑龙江省教育厅海外学人科研资助项目(1153h17) （1153h17）
黑龙江省教育厅科学技术研究项目(11521300) （11521300）
牡丹江医学院科学技术研究项目(2010-22) （2010-22）
