河北医学2011，Vol.17Issue(8)：1077-1079,3.DOI:10.3969/j.issn.1006-6233.2011.08.035
阿奇霉素序贯疗法治疗中重度肺炎支原体肺炎临床疗效分析
The Efficacy of Sequential Therapy of Azithromycin in Patients with Moderate and Severe Mycoplasma Pneumonia
庞祥华 1吴学典1
作者信息
- 1. 广东省雷州市人民医院儿科,广东,雷州,524200
- 折叠
摘要
Abstract
Objective: To explore the efficacy and feasibility of sequential therapy of azithromycin in patients with moderate and severe mycoplasma pneumonia ( MP). Method: 132 cases children with MP diagnosed in our hospital from Jan. 2008 to Jan. 2010, were divided into first group and second group. The patients in first group were infused 10rog/kg. d azithmmycin once a day for 5 days. Then infused again for another 5 days after 3 days drug-withdrawal. The second group were infused 10rog/kg. d azithromycin once a day for 3 days, then took it orally at the fourth day with 10rog/kg. d for 3 days. 4 days after drug-withdrawal, took it for another 3 days. Then observed the children's body temperature, cough pulmonary rale and side effect, Examed the chest X-my and liver function on the 16th days. Result:60 cases and 44 cases were cured in the first and second group. There's no significant difference in cure rate between two group ( X2 =0.185 P＞0.05), and so were the time of disappearing of cough pulmonary rate, etc. There's no significant difference in gastrointestinal reaction and the occure rate of rash. While , there's obviouse differece in the damage of liver function ( X2 = 5.22, P＜0.05 ). Conclusion: Comparing with infusion of azithromycin the damage of liver function and the local pain of intravenouse are obviously lower in the second group.关键词
阿奇霉素/肺炎支原体肺炎/序贯疗法Key words
Azithromycin/ Mycoplasma pneumonia/ Sequential therapy引用本文复制引用
庞祥华,吴学典..阿奇霉素序贯疗法治疗中重度肺炎支原体肺炎临床疗效分析[J].河北医学,2011,17(8):1077-1079,3.
