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糖尿病肾病患者糖化血清蛋白测定的意义

李沛霖 杨锐 周勇 陈宏 蔡德鸿

南方医科大学学报2011,Vol.31Issue(6):1093-1094,2.
南方医科大学学报2011,Vol.31Issue(6):1093-1094,2.

糖尿病肾病患者糖化血清蛋白测定的意义

Clinical significance of glycosylated serum protein in patients with diabetic nephropathy

李沛霖 1杨锐 1周勇 2陈宏 1蔡德鸿1

作者信息

  • 1. 南方医科大学珠江医院内分泌科,广东,广州,510280
  • 2. 佛山市明景糖尿病医院,广东,佛山,528300
  • 折叠

摘要

Abstract

Objective To explore the relations between fasting blood glucose (FBG), glycosylated hemoglobin Ale (HbAlc) and glycosylated serum protein (GSP). Methods FBG, HbAlc and GSP were measured in 303 patients with diabetic nephropathy and in 167 non-diabetic patients with comparable baseline data, and the correlations between FBG, HbAlc and GSP were analyzed. Results GSP levels were significantly higher in patients with diabetic nephropathy than in the non-diabetic patients (P<0.01). In patients with diabetic nephropathy, GSP levels were found to positively correlate to FBG (r=0.606) and HbAlc (r=0.733). Conclusions Patients with diabetic nephropathy show strong correlations between FBG, HbAlc and GSP. GSP detection is convenient, stable, and practical in evaluating the average FBG over a short term, which reduces the interference by FBG fluctuations in conventional blood glucose monitoring.

关键词

糖尿病肾病/糖化血清蛋白/糖化血红蛋白

Key words

diabetic nephropathy/ glycosylated serum protein/ glycosylated hemoglobin Ale

分类

医药卫生

引用本文复制引用

李沛霖,杨锐,周勇,陈宏,蔡德鸿..糖尿病肾病患者糖化血清蛋白测定的意义[J].南方医科大学学报,2011,31(6):1093-1094,2.

基金项目

广州市科技计划项目(2007Z055) (2007Z055)

南方医科大学学报

OA北大核心CSCDCSTPCD

1673-4254

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