中国临床医学2011，Vol.18Issue(3)：365-366,2.
甲钴胺联合前列地尔治疗糖尿病周围神经病变的疗效观察
Effects of Combination of Mecobalamin and Alprostadil on Diabetic Peripheral Neuropathy
周琳 1陈菊萍 1王丹丹 1赵一鸣 2刘玲 1杨玲1
作者信息
- 1. 上海市浦南医院内分泌科,上海,200125
- 2. 复旦大学附属中山医院肝外科,上海,200032
- 折叠
摘要
Abstract
Objective:To observe the effects of combination of mecobalamin and alprostadil (PGE1), mecobalamin only and vitamin 12 only on the patients with diabetic peripheral neuropathy (DPN). Methods: A total of 60 patients with DPN were divided into three groups (Group1, Group 2, and control group). Twenty patients in group1 were given mecobalamin (0. 5 mg IM. qd. ) and alprostadil (10 tg Ⅳ. qd. ) for consecutive 2 weeks. Twenty patients in Group2 were only given mecobalamin (0. 5 mg IM. qd. ) for consecutive 2 weeks. Twenty patients in control group were only given vitamin (0. 5 mg IM. qd. ) for consecutive 2 weeks. All patients were received adjuvant therapy with salvia injection. Results: Compared with control group, complains and physical signs of patients and every nerve conduction velocity (NCV) improved. The effects of Groupl were better than that of Group2. No side effect was found in three groups. Conclusions: The combination of mecobalamin and alprostadil could obtain better effects in patients with DPN.关键词
甲钴胺/前列地尔/糖尿病周围神经病变Key words
Mecobalamin/ Alprostadil/ Diabetic peripheral neuropathy分类
医药卫生引用本文复制引用
周琳,陈菊萍,王丹丹,赵一鸣,刘玲,杨玲..甲钴胺联合前列地尔治疗糖尿病周围神经病变的疗效观察[J].中国临床医学,2011,18(3):365-366,2.
