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甘精胰岛素对老年2型糖尿病患者β细胞功能的影响

毕明慧

中国临床医学2011,Vol.18Issue(3):367-368,2.
中国临床医学2011,Vol.18Issue(3):367-368,2.

甘精胰岛素对老年2型糖尿病患者β细胞功能的影响

The Effects of Insulin Glargine in Elderly Patients with Newly Diagnosed Type 2 Diabetes on β-Cell Function

毕明慧1

作者信息

  • 1. 上海市徐汇区中心医院老年病科,上海,200031
  • 折叠

摘要

Abstract

Objective:To investigate the effects of insulin glargine in elderly patients with newly diagnosed type 2 diabetes on βcell function. Methods:A total of 50 patients with newly diagnosed type 2 diabetics were randomly divided into two groups, the glargine treatment group (Group G) and aspart 30 treatment group (Group N). All patients were received treatment for 2 weeks. The islet β cell function index were calculated before and after the treatment. Results: Islet function in both groups had some degree of improvement, compared with before treatment were significantly different (P<0. 001). However after treatment, the delta I30/delta G30 ratio (ΔI30/ΔG30 ) in Group N were obviously improved more than in Group G (P<0. 05). Conclusions:For the newly diagnosed elderly patients with type 2 diabetes, early using of insulin glargine will help to improve the islet β-cell function.

关键词

2型糖尿病/胰岛功能/甘精胰岛素

Key words

Type 2 diabetes/ Islet function/ Insulin glargine

分类

生物科学

引用本文复制引用

毕明慧..甘精胰岛素对老年2型糖尿病患者β细胞功能的影响[J].中国临床医学,2011,18(3):367-368,2.

中国临床医学

OACSTPCD

1008-6358

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