中国临床医学2011，Vol.18Issue(3)：369-370,2.
垂体瘤术后成人生长激素缺乏症的临床研究
Clinical Analysis of Adult Growth Hormone Deficiency on the Postoperative Patients with Pituitary Adenoma
蒋翠萍 1叶红英 2赵雪兰 2胡仁明 2苗青 2张琼月 2张朝云 2李益明2
作者信息
- 1. 复旦大学附属华东医院内分泌科,上海,200040
- 2. 复旦大学附属华山医院内分泌科,上海,200040
- 折叠
摘要
Abstract
Objective:To study the reserve function of growth hormone (GH), the incidence rate of adult growth hormone deficiency (AGHD) and its correlation factors in the postoperative patients with pituitary adenoma.Methods: The insulin tolerance test (ITT)was performed in the postoperative patients with pituitary adenoma.Results: ITT was performed in 17 patients( 11 male, 6 female).The median age was 47.Only two patients had normal GH response, with fifteen severe deficient together with one or more than one kind of pituitary hormone deficiency.Among 17 cases, 11 cases were determined insulin-like growth factor-1 (IGF-1) meanwhile (9 normal, 2 decreased).Two cases with low IGF-1 level were confirmed as serious AGHD by ITT.Among the nine cases with normal IGF-1 level, two were confirmed normal by ITT, and the others as AGHD.Conclusions: There is a high incidence rate of AGHD in the postoperative patients with pituitary adenoma.AGHD often occurs in the patients with one or more than one kind of pituitary hormone deficiency.IGF-1 can not be used as a diagnose method of AGHD.关键词
垂体瘤/手术/随访/成人生长激素缺乏症Key words
Pituitary adenoma/ Surgery/ Follow-up/ Adult growth hormone deficiency分类
医药卫生引用本文复制引用
蒋翠萍,叶红英,赵雪兰,胡仁明,苗青,张琼月,张朝云,李益明..垂体瘤术后成人生长激素缺乏症的临床研究[J].中国临床医学,2011,18(3):369-370,2.
