计算机工程与应用2011，Vol.47Issue(18)：163-165,3.DOI:10.3778/j.issn.1002-8331.2011.18.047
蛋白质二级结构预测的一种新的编码方式
Novel coding scheme of protein secondary structure prediction
摘要
Abstract
Coding scheme plays an important role on determining the protein secondary structure prediction. A new compreheusive coding scheme is suggested to use for single-sequence protein secondary structure prediction. The method regards not only the trending factor of every amino acid appearance in protein secondary structure, but also the value of amino acid hydrophobicity,and it uses binary form to express all kinds of amino acid. The different code schemes are used to state the date set of CB513.Then,the theory of Support Vector Machine(SVM) is applied to protein secondary structure prediction.The results show that the prediction accuracy of the new coding scheme are about 1.48％ and 10.68％ higher than the classical orthogonal matrix and the five coding,respectively. It showes that this coding is more suitable for non-homologous or lower homologous protein structure prediction.关键词
编码方式/蛋白质二级结构预测/支持向量机Key words
coding scheme/protein secondary structure prediction/Support Vector Machine(SVM)分类
信息技术与安全科学引用本文复制引用
李汪根,叶小娇,黄尧颖..蛋白质二级结构预测的一种新的编码方式[J].计算机工程与应用,2011,47(18):163-165,3.基金项目
国家自然科学基金(the National Natural Science Foundation of China under Grant No.61070060). （the National Natural Science Foundation of China under Grant No.61070060）
