湖南中医药大学学报2011，Vol.31Issue(5)：51-53,3.DOI:10.3969/j.issn.1674-070X.2011.05.017.051.03
鸦胆子油乳经胸腔热灌注治疗恶性胸腔积液的临床研究
Clinical study of kosum grease emulsion via perfusion for malignant pleural effusion
摘要
Abstract
Objective To evaluate the clinical efficacy of kosum gease emulsion via perfusion for the malignant pleural effusion.Methods 30 patients with malignant pleural effusion were drained with the chest drainage tube, then, the normal saline 800～1000 mL at 45 ℃ was instilled, after retaining 20 minutes, the saline was drained fully, repeated 3 times, and in the final time, the 45 ℃ saline 100 mL+Dexamethasone 15 mg+kosum grease emulsion 60 mL was instilled into the chest, which was compared with that 30 patients treated with pleural chemotherapy, after pleural drainage, the warm saline 100 mL+dexamethasone 15 mg+cisplatin 50 mg/m2 was instilled, 1 time 1 week, total twice.Results The total effective rate was 86.7％ in treatment group, 63.3％ in control group (P=0.030); according to Karnofsky standard score, the life quality of patients in both groups was improved after treatment(all P=0.001); in which, the patient in treatment were more obvious (P=0.002); the incidences of side effects in treatment group were significantly reduced than that in control group (P=0.048).Conclusion Kosum grease emulsion via infusion for malignant pleural effusion is effective which can improve the life quality of patients and lower the side effects.关键词
恶性胸腔积液/鸦胆子油乳/热灌注Key words
malignant pleural effusion/ kosum grease emulsion/ infusion分类
医药卫生引用本文复制引用
曾普华,蒋益兰,蔡美,潘敏求..鸦胆子油乳经胸腔热灌注治疗恶性胸腔积液的临床研究[J].湖南中医药大学学报,2011,31(5):51-53,3.基金项目
国家中医药管理局重点学科(中医肿瘤病学)人才培养基金资助(2010). （中医肿瘤病学）
