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2例慢性肉芽肿病临床特征和中性粒细胞功能测定

杨晓旭 农光民 蒋敏

广西医科大学学报2011,Vol.28Issue(3):382-385,4.
广西医科大学学报2011,Vol.28Issue(3):382-385,4.

2例慢性肉芽肿病临床特征和中性粒细胞功能测定

CLINICAL FEATURES AND FLOW CYTOMETRY ASSAY OF 2 CHRONIC GRANULOMATOUS DISEASE

杨晓旭 1农光民 2蒋敏2

作者信息

  • 1. 广西医科大学
  • 2. 广西医科大学第一附属医院儿科,南宁530021
  • 折叠

摘要

Abstract

Objective:In this study, we investigated the clinical features of 2 chronic granulomatous disease children from 2 unrelated families of Guangxi,and analyzed their the neutrophil oxidative index by flow cytometry-DHR assay. Methods: we collected the clinical data of 2 chronic granulomatous disease children who had been diagnosed clinically in 2005 and 2010, at the same time, used their peripheral blood to test neutrophil function by flow cytometry. Results:Both children were boys, T and B cell counts of peripheral blood were normal, serum immunoglobulin levels were increased. Conclusion: For 2 children, the changes of their clinical symptomses met CGD diagnosed standard, and flow cytometry test comfirded that the neutrophil function was defect.

关键词

慢性肉芽肿病/NADPH氧化酶/呼吸爆发/流式细胞术

Key words

chronic granulomatous disease/ nicotinamide adenine dinucleotide phosphate oxidase/ respiratory burst/ flow cytometry

分类

医药卫生

引用本文复制引用

杨晓旭,农光民,蒋敏..2例慢性肉芽肿病临床特征和中性粒细胞功能测定[J].广西医科大学学报,2011,28(3):382-385,4.

基金项目

广西科技攻关项目(No.桂科攻0632007-1F) (No.桂科攻0632007-1F)

广西医科大学学报

OACSTPCD

1005-930X

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