广西医科大学学报2011,Vol.28Issue(3):382-385,4.
2例慢性肉芽肿病临床特征和中性粒细胞功能测定
CLINICAL FEATURES AND FLOW CYTOMETRY ASSAY OF 2 CHRONIC GRANULOMATOUS DISEASE
摘要
Abstract
Objective:In this study, we investigated the clinical features of 2 chronic granulomatous disease children from 2 unrelated families of Guangxi,and analyzed their the neutrophil oxidative index by flow cytometry-DHR assay. Methods: we collected the clinical data of 2 chronic granulomatous disease children who had been diagnosed clinically in 2005 and 2010, at the same time, used their peripheral blood to test neutrophil function by flow cytometry. Results:Both children were boys, T and B cell counts of peripheral blood were normal, serum immunoglobulin levels were increased. Conclusion: For 2 children, the changes of their clinical symptomses met CGD diagnosed standard, and flow cytometry test comfirded that the neutrophil function was defect.关键词
慢性肉芽肿病/NADPH氧化酶/呼吸爆发/流式细胞术Key words
chronic granulomatous disease/ nicotinamide adenine dinucleotide phosphate oxidase/ respiratory burst/ flow cytometry分类
医药卫生引用本文复制引用
杨晓旭,农光民,蒋敏..2例慢性肉芽肿病临床特征和中性粒细胞功能测定[J].广西医科大学学报,2011,28(3):382-385,4.基金项目
广西科技攻关项目(No.桂科攻0632007-1F) (No.桂科攻0632007-1F)