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甜味觉对大鼠弓状核NPY及FOS表达的影响

朱永香 王倩 王爽 贾敏 杨颖 于玮 曹健 南瑛

陕西医学杂志2011,Vol.40Issue(7):778-781,4.
陕西医学杂志2011,Vol.40Issue(7):778-781,4.

甜味觉对大鼠弓状核NPY及FOS表达的影响

The effect of sweet taste stimulation on neuropeptide Y and FOS expression in the arcuate nucleus of the rat

朱永香 1王倩 1王爽 2贾敏 3杨颖 3于玮 1曹健 1南瑛1

作者信息

  • 1. 西安医学院生理学教研室,西安,710021
  • 2. 西安医学院病理生理教研室
  • 3. 西安医学院科研中心
  • 折叠

摘要

Abstract

Objective : To investigate the effect of sweet taste stimulation on neuropeptide Y and Fos expression in the arcuate nucleus of the rats.Methods: The experimental group rats intook sucrose solution 15mL , and the control group rats intook distilled water 15mL , 2 hours later, the expression of neuropeptide Y and Fos in the arcuate nucleus was detected by immunohistochemistry.Using statistical software to analyze the difference of neuropeptide Y and Fos expression in the arcuate nucleus between the experimental group and the control group.Results: Compared with the control group, neuropeptide Y and Fos expression in the arcuate nucleus in the experimental group rats significantly increased.Conclusion: Appetite-promoting effect of the sweet taste food may be related to activation of the arcuate nucleus NPY neurons and up-regulation of NPY.

关键词

弓状核/神经肽Y/免疫学/FOS/味觉/大鼠

Key words

Arcuate nucleus/ Neuropeptide Y/immunology/ @Fos/ Taste/ Rats

分类

医药卫生

引用本文复制引用

朱永香,王倩,王爽,贾敏,杨颖,于玮,曹健,南瑛..甜味觉对大鼠弓状核NPY及FOS表达的影响[J].陕西医学杂志,2011,40(7):778-781,4.

基金项目

陕西省卫生厅科研基金资助项目(2010D57) (2010D57)

西安医学院校级课题(2007QN05) (2007QN05)

陕西医学杂志

OACSTPCD

1000-7377

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