实用临床医药杂志2011，Vol.15Issue(11)：99-100,105,3.
帕米膦酸二钠联合同期化疗治疗乳腺癌骨转移临床疗效观察
Clinical study of Pamidronate Disodium combined with concurrent chemotherapy for breast cancer with bone metastasis
杨兰平 1黄汉生1
作者信息
- 1. 广西壮族自治区柳州市肿瘤医院,化疗科,广西,柳州,545000
- 折叠
摘要
Abstract
Objective To evaluate the curative effect of Pamidronate Disodium combined with concurrent chemotherapy for the treatment of breast cancer patients with bone metastases.Methods Seventy- nine patients with metastatic tumor of bone were randomly divided in to Binin group (40 cases) and control group (39 cases). The Bonin group received 90 mg Pamidronate by intravenon infusion combined with concurrent chemotherapy; the control group was only treated with concurrent chemotherapy. Results The overall response rates of the Bonin group and control group were 96.8 ％ and 74.2 ％, respectively (P ＜ 0.05). The overall response rate of movement capacity improvement was 90.0 ％ in the Binin group and 74.4 ％ in the control group (P ＜ 0.05 ). The overall response rate of the life quality improvement was 87.5 ％ in the Bonin group and 64.1％ in the control group (P ＜ 0.05). The overall response rate of bone mineral density recovery was 75.50 ％ in the Bonin group and 43.59 96 in the control group ( P ＜ 0.05). Conclusion Bonin combined with concurrent chemotherapy can remarkably relieve bone pain, improve life quality, bone mineral density in breast cancer patients with bone metastases.关键词
骨转移癌/帕米膦酸二钠/化疗Key words
metastatic bone tumor/ Pamidronate Disodium/ chemotherapy分类
医药卫生引用本文复制引用
杨兰平,黄汉生..帕米膦酸二钠联合同期化疗治疗乳腺癌骨转移临床疗效观察[J].实用临床医药杂志,2011,15(11):99-100,105,3.
