中国中西医结合杂志2011，Vol.31Issue(7)：873-879,7.
采用国际生活质量量表评价中医药治疗老年晚期非小细胞肺癌的疗效
Assessment of Therapeutic Efficacy on Treating Advanced Non-small Cell Lung Cancer in the Aged by Chinese Medicine Adopting the International Questionnaire of Quality of Life
摘要
Abstract
Objective To assess the therapeutic efficacy of treating advanced non-small cell lung cancer (NSCLC) in the aged by Chinese medicine (CM) adopting the intemationai questionnaire of quality of life (QOL).Methods 91 aged patients with advanced NSCLC were randomly assigned to three groups. There were 31 in the CM group (Group Ⅰ), 30 in the chemotherapy group (Group Ⅱ), and 30 in the CM and chemotherapy combination group (Group Ⅲ). Oral administration of CM decoction and intravenous dripping of Chinese patent medicine was given to those in Group Ⅰ. Patients in Group Ⅱ received chemotherapeutic protocol alone. Patients in Group Ⅲ received chemotherapeutic protocol while orally taking CM decoction. Twenty-eight days were taken as one therapeutic course, and two courses in total. Assessment was performed using European Organization for Research and Treatment of Lung Cancer Quality of Life Questionnaire LC-43 (EORTC QLQ-LC43 ) before treatment, the 10th day of the second therapeutic course, and the 28th day of the second therapeutic course, respectively. Results After two therapeutic courses of treatment, compared with Group Ⅱ, better effects were obtained in Group Ⅰ and Group Ⅲ in the aspects of the physical function, roles function, emotional functions, social functions, general health state, and short breath, cough, fatigue,insomnia, poor appetite, and constipation (P＜0.05, P＜0.01). Conclusions CM therapy could relieve the clinical symptoms of aged patients with advanced NSCLC and improve their QOL.关键词
中医药疗法/晚期非小细胞肺癌/老年患者/生活质量Key words
Chinese medicine therapy/ advanced non-small cell lung cancer/ aged patient/ quality of life引用本文复制引用
单孟俊,韩宝惠,游捷..采用国际生活质量量表评价中医药治疗老年晚期非小细胞肺癌的疗效[J].中国中西医结合杂志,2011,31(7):873-879,7.基金项目
民政部中国老年学学会科研课题(No.2008-47-2-41) （No.2008-47-2-41）
