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异甘草酸镁治疗药物性肝损害的临床疗效探讨

郭换珍 安纪红 倪文 米林香 张亚丽

实用临床医药杂志2011,Vol.15Issue(13):75-76,2.
实用临床医药杂志2011,Vol.15Issue(13):75-76,2.

异甘草酸镁治疗药物性肝损害的临床疗效探讨

Exploration of therapeutic effects of Magnesuim Isoglycyrrhizinate on drug-induced liver injury

郭换珍 1安纪红 1倪文 1米林香 1张亚丽1

作者信息

  • 1. 内蒙古自治区医院,感染科,内蒙古,呼和浩特,010017
  • 折叠

摘要

Abstract

Objective To explore the therapeutic effects of City Magnesium Isoglycyrrhizinate on resistance against drug - induced liver injury.Methods Twenty - four patients in hospital were randomly divided into treatment group( 12 cases) and control group (12 cases).Both groups were given routine protection of liver.Treatment group was added the injection of Magnesium Isoglycyrrhizinate of 1.0 g and glucose of 250 ml once everyday for one month.The changes between pre-treatment and post- treatment in ALT, AST, TBIL, GGT, ALP and inpatient days were observed.Results Compared with control group, the liver function indices of treatment group improved obviously (P < 0.01 ), and the impatient days were shorter as well (P < 0.01 ).Conclusion The Magnesuim Isoglycyrrhizinate has excellent effects on resistance against drug - induced liver injury.It is worthy of further clinical application.

关键词

异甘草酸镁/药物性肝损害

Key words

Magnesuim Isoglycyrrhizinate/ drug- induced liver injury

分类

医药卫生

引用本文复制引用

郭换珍,安纪红,倪文,米林香,张亚丽..异甘草酸镁治疗药物性肝损害的临床疗效探讨[J].实用临床医药杂志,2011,15(13):75-76,2.

实用临床医药杂志

OACSTPCD

1672-2353

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